Complete surface control of peptide nanospheres with detachable and attachable polymer brush layers.
نویسندگان
چکیده
The surfaces of biodegradable peptide nanospheres with density-controllable poly(ethylene glycol) (PEG) brush layers were amenable to high levels of control, from hydrophilic 'stealth' properties to hydrophobic adsorptive properties depending on the PEG density in response to environmental conditions -'intelligent' properties that are expected to be useful for novel drug delivery systems.
منابع مشابه
2010: Stability of Biodegradable Peptide anospheres with PEG Brush Layer for Hydrolysis and Sterilization
Statement of Purpose: Polymeric nanoparticles have been widely studied in biomedical fields such as the drug delivery system (DDS), medical diagnosis, and bioimaging. For the long-term drug delivery system, stability for hydrolysis, stealth property for inhibition of unspecific protein adsorption, and surface functionality for immobilization of specific molecules to target tissues are required....
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ورودعنوان ژورنال:
- Chemical communications
دوره 46 37 شماره
صفحات -
تاریخ انتشار 2010